Bio X4 Review from Nucific – For Weight Loss and Improved Digestion

Last updated on February 2nd, 2019

Bio X4




Formula / Ingredients


Safety Rating


Customer Feedback


Value For Money



  • Made by respectable company
  • Good for digestive issues
  • Good set of ingredients
  • Postive customer feedback


  • Not the greatest for weight loss

Nucific Bio X4

This Bio X4 report will give you the benefits of taking the supplements, it’s formula, usage instruction and any side effects.

I will also list the customer opinion by giving some sampleBio X4 customer comments.

I will also highlight the most cost effective way of purchases and from where

  • Bio x4 can give you protection from bloating and gas
  • There are also hunger suppressing ingredients in the formula
  • Excellent customer comments as a digestive aid
  • Where to buy Bio X4 – cheapest prices, coupon codes – See bottom of page

Bio X4 is a food supplement produced in California by Nucific.

It comes in the form of vegetarian-friendly soft-gel capsules that provide a mix of probiotic bacteria, digestive enzymes, and plant extracts that have been taken from sustainable sources and are intended to promote weight loss and improved digestion and intestinal health.

Editors Note: We review and rate hundreds of supplements - which diet supplement is most popular and most effective. The top choice for 2019 - Click to find out

Potential BIO X4 Benefits

If the marketing material is to be believed, users of the product should be able to lose weight without the need for extreme lifestyle changes, difficult diet plans, or prescription medication.

  • Hunger reduction and control of the cravings that lead to overeating
  • Faster metabolism and increased fat burning
  • Protection from bloating and gas
  • Better nutrient and energy extraction (from food)
  • Increased self-confidence
  • No chemicals, lactose or fillers

Potential BIO X4 Benefits

Bio X4 Ingredient Profile

Each (1 capsule) dose provides:

Craving Control Blend

  • Slimaluma (166mg)

Weight Management Blend

  • Green Tea (100mg)

Digestive Enzyme Blend (43mg)

  • Bromelain
  • Amylase
  • Lipase

Probiotic Blend (4 Billion Bacteria)

  • Bifidobacterium blend (B. lactis, B. animalis)
  • Lactobacillus acidophilus blend (L. rhamnosus, L. acidophilus, L. planterum) 

Bio X4 Ingredient Profile

Bio X4 Formula

Can a single ingredient really be classed as a blend? Nucific obviously think so.

However, the ingredient chosen to power the Craving Control Blend is a good one.

Slimaluna is a patent-protected Caralluma fimbriata extract.

It won’t offer much in the way of protection against sugar cravings, so it’s a pity Nucific never thought to add some chromium or green coffee bean extract to pick up the slack.

Caralluma Fimbriata Supplements - Appetite Suppressant

Caralluma fimbriata has proven appetite suppressing abilities though, so it is good for controlling normal hunger.

Most studies involve doses of 1000mg per day.

Three Bio X4 capsules will only provide 498mg per day and this may not be enough to deliver the strong appetite suppression most dieters need.

Six capsules a day will be about right, but customers using such a dose will find this a very expensive product to use because each bottle will only be good for two weeks.

Weight Management Blend

The Weight Management Blend is also a one-shot wonder but, once again, Nucific have chosen a good ingredient to use.

Green tea is a proven metabolism booster and fat burner that has been shown to provide 24-hour weight loss support.

As with Caralluma fimbriata, six capsules per day will be necessary to provide an effective dose.

Digestive Blend

The Digestive Blend offers more questionable benefits and we have to wonder if it has already caused problems for some users in the past because the present 43mg inclusion rate is significantly less than the 88mg provided by earlier versions of the product.

The three enzymes provided are naturally occurring in the human digestive system.

Bromelain has the job of breaking down protein, amylase is responsible for processing carbohydrate, and lipase does the same with dietary fat.

These enzymes are sometimes added to supplements because their presence can help the body extract extra calories and nutrients from food.

By increasing energy extraction, they are more likely to contribute to weight gain than weight loss and could be seen to be working against Caralluma fimbriata and green tea.

Most diet pills block the action of digestive enzymes rather than increase their potency. Carb blockers inhibit amylase and many fat blockers work by inhibiting lipase.

Probiotic Blend

Probiotic supplements and products have become very popular because they provide the body with bacteria that’s known to improve intestinal health.

They help the body absorb the nutrients released by the digestive enzymes.

The forms provided by the Probiotic Blend in use here are pretty standard and can be found in any number of other products.

People who take six capsules per day will be increasing their bacteria count by 24 billion and we are not sure this is wise.

Recommended Dose and Other Usage Considerations

The normal dose is one capsule.

Three doses are required per day and should be timed to correspond with the three main meals of the day.

Taking the pills at meal times will ensure the digestive enzymes and probiotic bacteria provide maximum benefits.

Nucific state customers can take two capsules, three times per day if they wish to do so, but warn against taking more than six capsules per day.

We were surprised to see the marketing material fails to issue a warning against using the product while pregnant or nursing a child.

This is a serious omission because it would be highly unwise to use a product of this nature while pregnant or nursing.

As with any other supplements, people who have existing health problems or are using medication will need to ask their doctor for advice before using Bio X4.

Possible BIO X4 Side Effects

You are unlikely to experience any side effects.

Probiotic products may not be suitable for people who have weak immune systems or other underlying health issues.

A minority of probiotic users may also find they experience bloating, digestive problems, headaches and other negative issues, especially during the early stages of use.

Although side effects are rare, some people experience itching, tightness of the chest, breathlessness, and other side effects due to the use of orally-taken digestive enzymes. Potential users who have doubts about the product’s suitability are advised to seek the advice of a doctor prior to commencing supplementation.

BIO X4 Customer Opinion

The Nucific website provides a lot of positive feedback for the product.

The majority of users appear to value Bio X4 for it’s ability to improve digestive health rather than it’s weight loss benefits

A few average customer comments read:

“No more bloating or constipation. I’ve been clear of both for months. What a fantastic discovery.”

“This is the only product I’ve found that is good at keeping my IBS under control.”

“It’s so good to be able to just get on with enjoying my life instead of having to worry about whether or not certain food will upset my delicate digestive system.” 

“This is a truly amazing product. It’s allowed me to start enjoying all the foods I used to have to avoid because they upset my stomach.”

Guarantee and After-Sales Service

Nucific customers are provided with a generous 90-day money back guarantee.

Customer support is available via telephone during normal business hours.

It is also possible to contact the customer services department via email.

A mailing address is provided as well, but this more likely to be of interest to customers who wish to make product returns.

To Sum Up Bio X4

Nucific is an excellent company responsible for some very good products.

Customer reviews suggest Bio X4 may have a lot to offer to people who are suffering from certain digestive problems.

It is unlikely to provide much support to anyone who needs help to lose weight unless it is being used at the maximum dose of six capsules per day.

This will provide more realistic doses of Caralluma fimbriata and green tea. Unfortunately, it will also double the monthly cost of using the product.

More worryingly, a dose of six capsules per day may increase the chances of side effects by providing overly high doses of probiotic bacteria and digestive enzymes.

All things considered, we do not consider Bio X4 to be a viable weight loss product.

Places to Buy Bio X4

Like all Nucific products, it’s only possible to buy Bio X4 from the manufacturer’s website.

For latest pricing and valid coupon codes please visit official website.

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About Tony Jay 41 Articles
Tony Jay is the CEO of AGJ Media. He has 12 years experience in web content procurement specializing in the health, nutrition and wellness sector. Tony has a wealth of experience in the fitness sector attending many conferences across the world. Read more About Tony.


  1. I ordered a bottle on Dec 31/18 & have NOT received it yet? No email saying it’s on the way either?? Please look into it & let me know. Thx.
    Laurette Rostie

    • Hi Laurette, I’m Naomi from Nucific. I’m so sorry to hear that you have not received your package yet! I’d like to look into this right away. Please e-mail me directly at and I can track down your package. I’ll keep a lookout for your e-mail!

  2. I just watched a lengthy video on Bio-X4 and wanted to check on the product before deciding whether or not to purchase it. I am so excited to see these very fair-sounding reviews on the top weight loss supplements. Thank you

  3. This product does not work i used for 56 days straight!! I even increased and started to take 2 still NOTHING … continued to try since it comes with a 90 day guarantee when i called for the guarantee they said I had to have the empty bottles CRAP after talking to CS I went back to the website i ordered from to see as well as my order page NOWHERE ON THERE DOES IT SAY TO KEEP BOTTLES …

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